Genome Biology

official impact factor 6.89

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Transcriptome analysis of antigenic variation in Plasmodium falciparum - var silencing is not dependent on antisense RNA

Stuart A Ralph, Emmanuel Bischoff, Denise Mattei, Odile Sismeiro, Marie-Agnès Dillies, Ghislaine Guigon, Jean-Yves Coppee, Peter H David and Artur Scherf*

Genome Biology 2005, 6:R93 doi:10.1186/gb-2005-6-11-r93

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A global transcriptional analysis of Plasmodium falciparum malaria reveals a novel family of telomere-associated lncRNAs

Kate M Broadbent, Daniel Park, Ashley R Wolf, Daria Van Tyne, Jennifer S Sims, Ulf Ribacke, Sarah Volkman, Manoj Duraisingh, Dyann Wirth, Pardis C Sabeti, John L Rinn Genome Biology 2011, 12:R56 (20 June 2011)

Transcriptional analysis of Plasmodium falciparum reveals developmentally regulated telomere-associated lncRNAs

Research   Open Access

Simultaneous transcription of duplicated var2csa gene copies in individual Plasmodium falciparum parasites

Kim JM Brolin, Ulf Ribacke, Sandra Nilsson, Johan Ankarklev, Kirsten Moll, Mats Wahlgren, Qijun Chen Genome Biology 2009, 10:R117 (22 October 2009)

Duplicated var2csa genes in one strain of Plasmodium falciparum are simultaneously transcribed, challenging the dogma of mutual exclusive var gene transcription

Research   Open Access

CD36 selection of 3D7 Plasmodium falciparum associated with severe childhood malaria results in reduced VAR4 expression

Pamela A Magistrado, Trine Staalsoe, Thor G Theander, Lars Hviid, Anja TR Jensen Malaria Journal 2008, 7:204 (9 October 2008)

The antigens expressed at the surface of infected cells are critical virulence factors. The particular domain structure and sequence of each PfEMP1 determines its host-molecule binding phenotype. Whether binding occurs to host receptors in the brain or in other tissues is one of the factors that determine disease outcome. The data in this paper contribute to existing evidence.

Research article   Open Access

Dynamic RNA profiling in Plasmodium falciparum synchronized blood stages exposed to lethal doses of artesunate

Onguma Natalang, Emmanuel Bischoff, Guillaume Deplaine, Caroline Proux, Marie-Agnès Dillies, Odile Sismeiro, Ghislaine Guigon, Serge Bonnefoy, Jintana Patarapotikul, Odile Mercereau-Puijalon, Jean-Yves Coppée, Peter H David BMC Genomics 2008, 9:388 (18 August 2008)

Research article   Open Access

Serial Analysis of Gene Expression in Plasmodium berghei salivary gland sporozoites

Isabelle Rosinski-Chupin, Thomas Chertemps, Bertrand Boisson, Sylvie Perrot, Emmanuel Bischoff, Jérôme Briolay, Pierre Couble, Robert Ménard, Paul Brey, Patricia Baldacci BMC Genomics 2007, 8:466 (19 December 2007)

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Integration and mining of malaria molecular, functional and pharmacological data: how far are we from a chemogenomic knowledge space?

Lyn-Marie Birkholtz, Olivier Bastien, Gordon Wells, Delphine Grando, Fourie Joubert, Vinod Kasam, Marc Zimmermann, Philippe Ortet, Nicolas Jacq, Nadia Saïdani, Sylvaine Roy, Martin Hofmann-Apitius, Vincent Breton, Abraham I Louw, Eric Maréchal Malaria Journal 2006, 5:110 (17 November 2006)

A review of the different tools and strategies that have recently been developed to process the huge amount of data produced by the X-omic projects. This includes the comparison of protein sequences, high throughput reconstruction of molecular phylogenies, representation of biological processes, methods to integrate X-omic generated data following drug treatments and in silico prediction of protein structure and identification of specific ligand.