Table 2

Identification of splice junctions


Known trans-splicing regions
Known coding regions

Predicted splice sites
True positive
False positive

17
2.5

(10-22)
(0-4)



Predicted nonsplice sites
False negative
True negative

4.5
13.9

(1-8)
(11-16)




Sensitivity: 0.80
Specificity: 0.85

(0.71-0.93)
(0.75-1.00)




Accuracy: 0.82

(0.74-0.93)

The overall performance of the method in identifying splice junctions was determined by comparing the number of known splice junctions that were identified by the method in known trans-splicing regions versus those in known coding regions. These results are from tenfold cross-validation, and each test dataset had on average 21.5 known trans-splicing regions and 16.4 known coding regions.

Gopal et al. Genome Biology 2005 6:R95   doi:10.1186/gb-2005-6-11-r95

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