Genome Biology

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Chipper: discovering transcription-factor targets from chromatin immunoprecipitation microarrays using variance stabilization

Francis D Gibbons1, Markus Proft1,2, Kevin Struhl1 and Frederick P Roth1*

Author Affiliations

1 Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Longwood Avenue, Boston, MA 02115, USA

2 Instituto de Biología Molecular y Celular de Plantas (IBMCP), Universidad Politécnica de Valencia, Camino de Vera s/n, 46022 Valencia, Spain

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Genome Biology 2005, 6:R96 doi:10.1186/gb-2005-6-11-r96

Published: 1 November 2005

Additional files

Additional data File 1:

A tab-delimited file containing the results of our analysis for all intergenic regions studied in our experiments.

Format: TXT Size: 358KB Download file

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Additional data File 2:

A detailed description of the comparison between the targets of Sko1 identified by Chipper when applied both to the data presented here and to other Chip2 data [2], and previously published p values using a single-array error model [2].

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Additional data File 3:

A figure illustrating the comparisons made in Additional data file 2.

Format: PDF Size: 62KB Download file

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Additional data File 4:

A figure illustrating the comparisons made in Additional data file 2.

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Additional data File 5:

A figure comparing the two methods described in Additional data file 2 as applied to results from six additional transcription factors.

Format: PDF Size: 50KB Download file

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Additional data File 6:

A list of the intergenic regions identified as targets [29].

Format: TXT Size: 3KB Download file

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