Predicting the sites of metastases
Applied Genomics Inc., 525 Del Rey Avenue, Sunnyvale, CA 94085, USA
Genome Biology 2005, 6:241 doi:10.1186/gb-2005-6-12-241Published: 2 December 2005
Transplantation of human breast cancer cells into immunodeficient mice together with gene-expression microarray studies has recently identified genes implicated in the tissue tropism of breast-cancer metastasis. Such signatures of site-specific metastatic capabilities might allow the targeting of therapy to likely sites of metastasis.