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Biased alternative polyadenylation in human tissues

Haibo Zhang, Ju Y Lee and Bin Tian*

Author Affiliations

Department of Biochemistry and Molecular Biology, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, 185 South Orange Avenue, Newark, NJ 07101-1709, USA

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Genome Biology 2005, 6:R100 doi:10.1186/gb-2005-6-12-r100

Published: 28 November 2005

Additional files

Additional data file 1:

A PDF containing supplemental tables and figures. The tables list: Table 1, tissues, cDNA libraries, genes, ESTs, and poly(A) sites used in this study; Table 2, poly(A) site usage of type II genes; Table 3, poly(A) site usage of type III genes; Table 4, usage of strong and weak poly(A) sites using 60% as cutoff; Table 5, usage of strong and weak poly(A) sites using 75% as cutoff; Table 6, usage of strong and weak poly(A) sites using 90% as cutoff. The figures show: Figure 1, Schematic representation of three types of genes; Figure 2, Boxplots of mRNA expression levels of polyadenylation-related factors in brain tissues versus other tissues; Figure 3, selection of hexamers in different poly(A) regions; Figure 4, multiple sequence alignments of PTB and nPTB and CstF-64 and Ï„CstF-64.

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