Genome Biology

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Primary and secondary transcriptional effects in the developing human Down syndrome brain and heart

Rong Mao, Xiaowen Wang, Edward L Spitznagel, Laurence P Frelin, Jason C Ting, Huashi Ding, Jung-whan Kim, Ingo Ruczinski, Thomas J Downey and Jonathan Pevsner*

Genome Biology 2005, 6:R107 doi:10.1186/gb-2005-6-13-r107

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Integrated analysis of DNA copy number and gene expression microarray data using gene sets

Renée X Menezes, Marten Boetzer, Melle Sieswerda, Gert-Jan B van Ommen, Judith M Boer BMC Bioinformatics 2009, 10:203 (29 June 2009)

Research article   Open Access

Gene expression signature of cerebellar hypoplasia in a mouse model of Down syndrome during postnatal development

Julien Laffaire, Isabelle Rivals, Luce Dauphinot, Fabien Pasteau, Rosine Wehrle, Benoit Larrat, Tania Vitalis, Randal X Moldrich, Jean Rossier, Ralph Sinkus, Yann Herault, Isabelle Dusart, Marie-Claude Potier BMC Genomics 2009, 10:138 (30 March 2009)

Research article   Open Access

Profiling expression changes caused by a segmental aneuploid in maize

Irina Makarevitch, Ronald L Phillips, Nathan M Springer BMC Genomics 2008, 9:7 (10 January 2008)

Research article   Open Access

Altered expression of mitochondrial and extracellular matrix genes in the heart of human fetuses with chromosome 21 trisomy

Anna Conti, Floriana Fabbrini, Paola D'Agostino, Rosa Negri, Dario Greco, Rita Genesio, Maria D'Armiento, Carlo Olla, Dario Paladini, Mariastella Zannini, Lucio Nitsch BMC Genomics 2007, 8:268 (7 August 2007)

Research   Open Access

Gene expression variation in Down's syndrome mice allows prioritization of candidate genes

Marc Sultan, Ilaria Piccini, Daniela Balzereit, Ralf Herwig, Nidhi G Saran, Hans Lehrach, Roger H Reeves, Marie-Laure Yaspo Genome Biology 2007, 8:R91 (25 May 2007)

RNA from eight Ts65Dn mice (a model of Down syndrome) and eight euploid mice were analysed by real-time PCR to examine inter-individual gene expression levels as a function of trisomy.

Research article   Open Access

Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21

Chi-Ming Li, Meirong Guo, Martha Salas, Nicole Schupf, Wayne Silverman, Warren B Zigman, Sameera Husain, Dorothy Warburton, Harshwardhan Thaker, Benjamin Tycko BMC Medical Genetics 2006, 7:24 (15 March 2006)

Differential over-expression of chromosome 21 genes in trisomy 21 fibroblasts and fetal hearts may help explain the occurrence of cardiac defects and autoimmune diseases in patients with Down syndrome.