Table 3

Under-translated osmoregulatory genes

Gene

Function

GCY1

Salt induced aldo-keto reductase

AQY1

Aquaporin

ALD3

Aldehyde dehydrogenase, activity increased by osmotic shock

BCK1

MAPKKK in the PKC pathway

HAL1

Halotolerance

MSN1

Present with Hot1p at GPD1 promoter only during osmostress

HAL5

Cation homeostasis

HOT1

Transcription factor, high osmolarity

NST1

Negative effector of halotolerance

SSK22

MAPKK osmosensing, redundant w/SSK2

SSK1

osmosensing activator of MAPK pathway

SSK2

MAPKK osmosensing

DOA4

Involved in vacuole biogenesis and osmoregulation

HOG1

MAPK in osmolarity response

DAK2

Glycerone kinase, response to stress

APA2

Osmoregulation in vacuole

PGM2

Osmoregulation

WSC3

Osmoregulation

This list of genes was derived from a Gene Ontology analysis of the translation state of transcripts of yeast cells growing in rich-glucose medium [3]. MAPK, mitogen-activated protein kinase; MAPKK, MAPK kinase; MAPKKK, MAPK kinase kinase; PKC, protein kinase C.

Law et al. Genome Biology 2005 6:R111   doi:10.1186/gb-2005-6-13-r111