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Open Access Software

iVici: Interrelational Visualization and Correlation Interface

Kirill Tarassov and Stephen W Michnick*

Author Affiliations

Département de Biochimie and Centre Robert-Cedergren, Bioinformatiques et Genomiques, Université de Montréal, CP 6128, Succursale Centre-ville, Montréal, Québec, H3C 3J7, Canada

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Genome Biology 2005, 6:R115  doi:10.1186/gb-2005-6-13-r115

Published: 30 December 2005

Abstract

We have developed an application, iVici, to analyze cellular networks represented as addressable symmetric or asymmetric two-dimensional matrices. iVici was designed to permit simultaneous visualization and correlation of multiple datasets, representing any relationship between a set of genes, mRNAs, or proteins. Visual overlay of datasets and addressable access to gene annotations permits comparison of networks of different types (for example protein-protein interactions and genetic networks) or investigation of the dynamic reorganization of a particular network.