Table 1

The human VEGF family and related proteins from Drosophila and Orf virus

Species (strain) and gene name

Number ofexons

Chromosomal location*

Accession number

References

Homologsfound in other species


Human VEGF-A

8

6p12

NM_003376

[59]

Mus musculus

Rattus norvegicus

Sus scrofa

Bos taurus

Canis familiaris

Gallus gallus

Xenopus laevis

Danio rerio

Fugu rubripes

Human VEGF-B

7

11q13

NM_003377

[23]

M. musculus

R. norvegicus

B. taurus

Human VEGF-C

7

4q34.1-q34.3

NM_005429

[60]

M. musculus

R. norvegicus

B. taurus

D. rerio

Human VEGF-D

7

Xp22.31

NM_004469

[61]

M. musculus

R. norvegicus

B. taurus

Human PLGF

7

14q24-q31

NM_002632

[22]

M. musculus

R. norvegicus

B. taurus

Orf virus (D1701) VEGF-E

-

-

AF106020

-

Orf virus (NZ2) VEGF-E

-

-

S67520

-

Orf virus (NZ7) VEGF-E

-

-

S67522

-

D. melanogaster PVF1

6

X 17E1-17E6

NM_078683

[14-16]

Caenorhabditis elegans§

Podocoryne carnea

D. melanogaster PVF2

5

2L 27E1

NM_078775

[16]

-

D. melanogaster PVF3

6

2L 27E1-27E2

NM_078776

[16]

-


*Chromosome locations of human and Drosophila genes are from Entrez Gene and FlyBase. Accession numbers are from RefSeq and GenBank.

Homolog data are from HomoloGene, Entrez Gene and [13].§Putative homolog identified by survey of C. elegans genome [17]. Possible homolog [18].

Holmes and Zachary Genome Biology 2005 6:209   doi:10.1186/gb-2005-6-2-209