Table 3

Genes upregulated with term activation


Gene symbol
Fold-change at 18 days

Regulation of cell growth


Inhibin beta-B
Inhbb
3.1
Inhibin beta-A
Inhba
2.2



Cell death


Growth arrest and DNA-damage-inducible 45 γ
Gadd45g
3.2
Baculoviral IAP repeat-containing 1a
Birc1a
2.1
Clusterin
Clu
2.0



Cell junctions


Occludin
Ocln
2.8
Gap junction membrane channel protein α1
Cx43
2.8
Desmoplakin
Dsp
2.8



G-protein signaling


Lysophosphatidic acid receptor Edg-2
Edg2
2.8
Guanine nucleotide binding protein, γ12
Gng12
2.1



Structural constituent of cytoskeleton


Villin 2
Vil2
3.1



Kinesin complex


Keratin complex 1, acidic, gene 19
Krt1-19
7.8
Keratin complex 2, basic, gene 7
Krt2-7
4.6
Keratin complex 2, basic, gene 8
Krt2-8
4.6
Keratin complex 1, acidic, gene 18
Krt1-18
4.5
Surfactant associated protein D
Sftpd
3.4



Metabolism and biosynthetic reactions


Lipoprotein lipase
Lpl
4.5
Aldehyde dehydrogenase family 1, subfamily A2
Aldh1a2
3.9
Glutathione S-transferase omega 1
Gsto1
3.7
Branched chain aminotransferase 1, cytosolic
Bcat1
3.4
Protein phosphatase 1, regulatory subunit 3C
Ppp1r3c
2.2
Carbonic anhydrase 2
Car2
2.1



Proteolysis and peptidolysis


Cytosolic nonspecific dipeptidase
0610010E05Rik
3.2
Transmembrane protease, serine 2
Tmprss2
2.1
Kallikrein 5
Klk5
2.1



Collagen catabolism


Peptidase 4
Pep4
2.3
Matrix metalloproteinase 7
Mmp7
2.2



Proteolysis inhibitors


Complement component 3
C3
4.3
RIKEN cDNA 1600023A02 gene
1600023A02Rik
2.9
Extracellular proteinase inhibitor
Expi
2.8



Transcriptional regulation


Transcription factors


Myeloblastosis oncogene
Myb
2.5
Hairy and enhancer of split 1
Hes1
2.3
E74-like factor 3
Elf3
2.1



Androgen regulation


Kidney androgen regulated protein
Kap
33.9
Heat shock protein 4
Hspa4
3.1
Alpha fetoprotein
Afp
3.1



Transport


FXYD domain-containing ion transport regulator 3
Fxyd3
2.8
Lipocalin 2
Lcn2
2.5
Lactotransferrin
Ltf
2.2
Solute carrier family 16, member 1
Slc16a1
2.1
Fatty acid binding protein 5, epidermal
Fabp5
2.0

Only upregulated genes with a relative fold-change of 2 or more versus non-pregnant mice at 18.5 days gestation and linked to biological categories highlighted by the expression analysis are shown. Full gene lists can be obtained online (see Additional data file 6).

Salomonis et al. Genome Biology 2005 6:R12   doi:10.1186/gb-2005-6-2-r12