Table 3 |
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|
Genes upregulated with term activation |
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|
Gene symbol |
Fold-change at 18 days |
|
|
|
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|
Regulation of cell growth |
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|
Inhibin beta-B |
Inhbb |
3.1 |
|
Inhibin beta-A |
Inhba |
2.2 |
|
Cell death |
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|
Growth arrest and DNA-damage-inducible 45 γ |
Gadd45g |
3.2 |
|
Baculoviral IAP repeat-containing 1a |
Birc1a |
2.1 |
|
Clusterin |
Clu |
2.0 |
|
Cell junctions |
||
|
Occludin |
Ocln |
2.8 |
|
Gap junction membrane channel protein α1 |
Cx43 |
2.8 |
|
Desmoplakin |
Dsp |
2.8 |
|
G-protein signaling |
||
|
Lysophosphatidic acid receptor Edg-2 |
Edg2 |
2.8 |
|
Guanine nucleotide binding protein, γ12 |
Gng12 |
2.1 |
|
Structural constituent of cytoskeleton |
||
|
Villin 2 |
Vil2 |
3.1 |
|
Kinesin complex |
||
|
Keratin complex 1, acidic, gene 19 |
Krt1-19 |
7.8 |
|
Keratin complex 2, basic, gene 7 |
Krt2-7 |
4.6 |
|
Keratin complex 2, basic, gene 8 |
Krt2-8 |
4.6 |
|
Keratin complex 1, acidic, gene 18 |
Krt1-18 |
4.5 |
|
Surfactant associated protein D |
Sftpd |
3.4 |
|
Metabolism and biosynthetic reactions |
||
|
Lipoprotein lipase |
Lpl |
4.5 |
|
Aldehyde dehydrogenase family 1, subfamily A2 |
Aldh1a2 |
3.9 |
|
Glutathione S-transferase omega 1 |
Gsto1 |
3.7 |
|
Branched chain aminotransferase 1, cytosolic |
Bcat1 |
3.4 |
|
Protein phosphatase 1, regulatory subunit 3C |
Ppp1r3c |
2.2 |
|
Carbonic anhydrase 2 |
Car2 |
2.1 |
|
Proteolysis and peptidolysis |
||
|
Cytosolic nonspecific dipeptidase |
0610010E05Rik |
3.2 |
|
Transmembrane protease, serine 2 |
Tmprss2 |
2.1 |
|
Kallikrein 5 |
Klk5 |
2.1 |
|
Collagen catabolism |
||
|
Peptidase 4 |
Pep4 |
2.3 |
|
Matrix metalloproteinase 7 |
Mmp7 |
2.2 |
|
Proteolysis inhibitors |
||
|
Complement component 3 |
C3 |
4.3 |
|
RIKEN cDNA 1600023A02 gene |
1600023A02Rik |
2.9 |
|
Extracellular proteinase inhibitor |
Expi |
2.8 |
|
Transcriptional regulation |
||
|
Transcription factors |
||
|
Myeloblastosis oncogene |
Myb |
2.5 |
|
Hairy and enhancer of split 1 |
Hes1 |
2.3 |
|
E74-like factor 3 |
Elf3 |
2.1 |
|
Androgen regulation |
||
|
Kidney androgen regulated protein |
Kap |
33.9 |
|
Heat shock protein 4 |
Hspa4 |
3.1 |
|
Alpha fetoprotein |
Afp |
3.1 |
|
Transport |
||
|
FXYD domain-containing ion transport regulator 3 |
Fxyd3 |
2.8 |
|
Lipocalin 2 |
Lcn2 |
2.5 |
|
Lactotransferrin |
Ltf |
2.2 |
|
Solute carrier family 16, member 1 |
Slc16a1 |
2.1 |
|
Fatty acid binding protein 5, epidermal |
Fabp5 |
2.0 |
|
|
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|
Only upregulated genes with a relative fold-change of 2 or more versus non-pregnant mice at 18.5 days gestation and linked to biological categories highlighted by the expression analysis are shown. Full gene lists can be obtained online (see Additional data file 6). |
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|
Salomonis et al. Genome Biology 2005 6:R12 doi:10.1186/gb-2005-6-2-r12 |
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