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Identity of tissue-specific genes with expression patterns consistent in all three populations, and those inconsistent in all three populations |
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| Gene (see Figure 7) |
Grid |
Short name |
Swiss-Prot name |
|
|
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| Consistent - oxidative phosphorylation |
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| a |
E8 |
Aldo keto reductase 1 A1 |
Aldo-keto reductase family 1 member A1 (aldehyde reductase) |
| b |
E7 |
Aldo keto reductase 1 D1 |
Aldo-keto reductase family 1 member D1; steroid-5-beta-reductase beta polypeptide 1 (3-oxo-5 beta-steroid delta 4-dehydrogenase beta 1); steroid 5-beta-reductase |
| c |
F1 |
G3PDH |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) |
| d |
D10 |
Glucose 6 phosphatase |
Glucose-6-phosphatase (G6PASE) |
| e |
H3 |
Pyruvate kinase muscle |
Pyruvate kinase (muscle isozyme) |
| f |
G10 |
Pyruvate kinase R |
Pyruvate kinase isoform R (erythroid) |
| g |
I6 |
NADH dehydrb 6 (17 kD) |
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 6 (17 kD B17) |
| h |
G4 |
NADH Ubiq Oxi ASHI |
NADH-ubiquinone oxidoreductase ASHI subunit precursor (complex I-ASHI) (CI-ASHI) |
| i |
M4 |
NADH Ubiq Oxi MNLL |
NADH-ubiquinone oxidoreductase MNLL subunit (complex I-MNLL) (CI-MNLL) |
| j |
L1 |
ATP syn H+ FO c 9 2 |
ATP synthase H+ transporting mitochondrial F0 complex subunit c (subunit 9) isoform 2 |
| k |
P3 |
ATP syn H+ FO F6 |
ATP synthase H+ transporting mitochondrial F0 complex subunit F6; coupling factor 6 |
| l |
I9 |
Cyto C oxi III |
Cytochrome c oxidase subunit III |
| m |
J10 |
Cyto C oxi VA |
Cytochrome C oxidase polypeptide VA |
| n |
N8 |
Cyto C oxi VIa |
Cytochrome c oxidase subunit VIa precursor polypeptide 2 |
| o |
J5 |
Cyto C oxi VIIC |
Cytochrome C oxidase polypeptide VIIC precursor (VIIIA) |
| p |
K12 |
Cyto C oxi VIIIb |
Cytochrome c oxidase subunit VIIIb |
| Consistent - other metabolism |
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| q |
H12 |
Isocitrate dehyd 2 |
Isocitrate dehydrogenase 2 (mitochondrial IDH2) |
| r |
A9 |
PEP carboxykinase |
PEP carboxykinase phosphoenolpyruvate carboxykinase |
| s |
D8 |
Fatty acid binding liver basic |
Liver-basic fatty acid binding protein (LB-FABP) |
| t |
B12 |
Delta 6 fatty acid desaturase |
Delta-6 fatty acid desaturase |
| u |
H1 |
Triglyceride lipase triacylglycerol |
Triglyceride lipase triacylglycerol |
| v |
I5 |
Glycerol kinase |
Glycerol kinase |
| w |
M10 |
Lipoprotein lipase |
Lipoprotein lipase |
| x |
P9 |
Phospholipase XIII A2 |
Group XIII secreted phospholipase A2 |
| y |
F4 |
Cystathionine beta synthase |
Cystathionine-beta-synthase |
| z |
K11 |
Cold inducible RNA binding |
Cold inducible RNA-binding protein; (CIRBP) glycine-rich RNA binding protein; |
| aa |
F2 |
Hepatocyte nuclear F 4 A |
Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (transcription factor HNF-4) |
| bb |
M1 |
p450 2P1 (CYP2P1) |
Cytochrome P450 2P1 (CYP2P1) |
| cc |
D6 |
Glutathione peroxidase 4 |
Glutathione peroxidase 4 (phospholipid hydroperoxidase) |
| dd |
O11 |
Methylmalonate semialdehyde dehyd |
Methylmalonate-semialdehyde dehydrogenase (acylating) |
| ee |
N7 |
Phosphatidylcholine sterol acyltrans |
Phosphatidylcholine-sterol acyltransferase |
| ff |
B1 |
Prostaglandin D syn |
Prostaglandin D synthase |
| Inconsistent - oxidative phosphorylation |
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| gg |
A6 |
ADH class II mito |
Aldehyde dehydrogenase, mitochondrial precursor (ALDH class 2) |
| hh |
E12 |
Aldolase 1 A |
Aldolase 1 A. muscle |
| ii |
A2 |
Enolase beta muscle |
enolase (beta muscle specific) |
| jj |
F7 |
LDHB |
lactate dehydrogenase B (LDHB) |
| kk |
O6 |
PFK |
6-phosphofructokinase |
| ll |
K4 |
NADH dehyd MLRQ |
NADH dehydrogenase (ubiquinone) MLRQ subunit (complex I-MLRQ) |
| mm |
L9 |
NADH dehyd I |
NADH dehydrogenase subunit 1 |
| nn |
C6 |
NADH dehydr a 1 (7.5 kD MWFE) |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1 (7.5 kD MWFE) |
| oo |
E6 |
NADH dehydr a 9 (39 kD) |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 9 (39 kD) |
| pp |
M6 |
ATP syn B |
ATP synthase subunit B |
| Inconsistent - other metabolism |
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| qq |
C7 |
Transketolase |
Transketolase |
| rr |
H8 |
Fatty acid binding 7 brain |
Fatty acid binding protein 7 brain (B-FABP) |
| ss |
A3 |
Fatty acid binding H6 |
Fatty acid binding protein H6-isoform |
| tt |
O10 |
Fatty acid binding heart |
Heart-type fatty acid-binding protein (H-FABP) |
| uu |
D9 |
Fatty acid syn |
Fatty acid synthase |
| vv |
F9 |
Glutamate decarboxylase |
Glutamate decarboxylase |
|
Letters in the first column refer to genes illustrated in Figure 7; the grid column identifies genes as reported in our data entry to the NCBI Gene Expression Omnibus (GLP1224). Gene identities are listed as those identified by Swiss-Prot and as shortened names, and grouped as genes involved in oxidative phosphorylation or in other biochemical pathways. | |||
Whitehead and Crawford Genome Biology 2005 6:R13 doi:10.1186/gb-2005-6-2-r13 |
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