Table 1

Identity of tissue-specific genes with expression patterns consistent in all three populations, and those inconsistent in all three populations

Gene (see Figure 7)

Grid

Short name

Swiss-Prot name


Consistent - oxidative phosphorylation

a

E8

Aldo keto reductase 1 A1

Aldo-keto reductase family 1 member A1 (aldehyde reductase)

b

E7

Aldo keto reductase 1 D1

Aldo-keto reductase family 1 member D1; steroid-5-beta-reductase beta polypeptide 1 (3-oxo-5 beta-steroid delta 4-dehydrogenase beta 1); steroid 5-beta-reductase

c

F1

G3PDH

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

d

D10

Glucose 6 phosphatase

Glucose-6-phosphatase (G6PASE)

e

H3

Pyruvate kinase muscle

Pyruvate kinase (muscle isozyme)

f

G10

Pyruvate kinase R

Pyruvate kinase isoform R (erythroid)

g

I6

NADH dehydrb 6 (17 kD)

NADH dehydrogenase (ubiquinone) 1 beta subcomplex 6 (17 kD B17)

h

G4

NADH Ubiq Oxi ASHI

NADH-ubiquinone oxidoreductase ASHI subunit precursor (complex I-ASHI) (CI-ASHI)

i

M4

NADH Ubiq Oxi MNLL

NADH-ubiquinone oxidoreductase MNLL subunit (complex I-MNLL) (CI-MNLL)

j

L1

ATP syn H+ FO c 9 2

ATP synthase H+ transporting mitochondrial F0 complex subunit c (subunit 9) isoform 2

k

P3

ATP syn H+ FO F6

ATP synthase H+ transporting mitochondrial F0 complex subunit F6; coupling factor 6

l

I9

Cyto C oxi III

Cytochrome c oxidase subunit III

m

J10

Cyto C oxi VA

Cytochrome C oxidase polypeptide VA

n

N8

Cyto C oxi VIa

Cytochrome c oxidase subunit VIa precursor polypeptide 2

o

J5

Cyto C oxi VIIC

Cytochrome C oxidase polypeptide VIIC precursor (VIIIA)

p

K12

Cyto C oxi VIIIb

Cytochrome c oxidase subunit VIIIb

Consistent - other metabolism

q

H12

Isocitrate dehyd 2

Isocitrate dehydrogenase 2 (mitochondrial IDH2)

r

A9

PEP carboxykinase

PEP carboxykinase phosphoenolpyruvate carboxykinase

s

D8

Fatty acid binding liver basic

Liver-basic fatty acid binding protein (LB-FABP)

t

B12

Delta 6 fatty acid desaturase

Delta-6 fatty acid desaturase

u

H1

Triglyceride lipase triacylglycerol

Triglyceride lipase triacylglycerol

v

I5

Glycerol kinase

Glycerol kinase

w

M10

Lipoprotein lipase

Lipoprotein lipase

x

P9

Phospholipase XIII A2

Group XIII secreted phospholipase A2

y

F4

Cystathionine beta synthase

Cystathionine-beta-synthase

z

K11

Cold inducible RNA binding

Cold inducible RNA-binding protein; (CIRBP) glycine-rich RNA binding protein;

aa

F2

Hepatocyte nuclear F 4 A

Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (transcription factor HNF-4)

bb

M1

p450 2P1 (CYP2P1)

Cytochrome P450 2P1 (CYP2P1)

cc

D6

Glutathione peroxidase 4

Glutathione peroxidase 4 (phospholipid hydroperoxidase)

dd

O11

Methylmalonate semialdehyde dehyd

Methylmalonate-semialdehyde dehydrogenase (acylating)

ee

N7

Phosphatidylcholine sterol acyltrans

Phosphatidylcholine-sterol acyltransferase

ff

B1

Prostaglandin D syn

Prostaglandin D synthase

Inconsistent - oxidative phosphorylation

gg

A6

ADH class II mito

Aldehyde dehydrogenase, mitochondrial precursor (ALDH class 2)

hh

E12

Aldolase 1 A

Aldolase 1 A. muscle

ii

A2

Enolase beta muscle

enolase (beta muscle specific)

jj

F7

LDHB

lactate dehydrogenase B (LDHB)

kk

O6

PFK

6-phosphofructokinase

ll

K4

NADH dehyd MLRQ

NADH dehydrogenase (ubiquinone) MLRQ subunit (complex I-MLRQ)

mm

L9

NADH dehyd I

NADH dehydrogenase subunit 1

nn

C6

NADH dehydr a 1 (7.5 kD MWFE)

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1 (7.5 kD MWFE)

oo

E6

NADH dehydr a 9 (39 kD)

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 9 (39 kD)

pp

M6

ATP syn B

ATP synthase subunit B

Inconsistent - other metabolism

qq

C7

Transketolase

Transketolase

rr

H8

Fatty acid binding 7 brain

Fatty acid binding protein 7 brain (B-FABP)

ss

A3

Fatty acid binding H6

Fatty acid binding protein H6-isoform

tt

O10

Fatty acid binding heart

Heart-type fatty acid-binding protein (H-FABP)

uu

D9

Fatty acid syn

Fatty acid synthase

vv

F9

Glutamate decarboxylase

Glutamate decarboxylase


Letters in the first column refer to genes illustrated in Figure 7; the grid column identifies genes as reported in our data entry to the NCBI Gene Expression Omnibus (GLP1224). Gene identities are listed as those identified by Swiss-Prot and as shortened names, and grouped as genes involved in oxidative phosphorylation or in other biochemical pathways.

Whitehead and Crawford Genome Biology 2005 6:R13   doi:10.1186/gb-2005-6-2-r13

Open Data