Genome Biology Volume 6 Issue 3 |
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OpinionFlexible peptides and cytoplasmic gelsDennis Bray  Department of Anatomy, University of Cambridge, Cambridge CB2 3DY, UK author email corresponding author email
Genome Biology 2005,
6:106doi:10.1186/gb-2005-6-3-106
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28 February 2005 |
Subject areas: Cell biology, Biochemistry and structural biology, Molecular biology Abstract
Recent progress in predicting protein structures has revealed a surprising abundance of proteins that are significantly unfolded under physiological conditions. Unstructured, flexible polypeptides are likely to be functionally important and may cause local cytoplasmic regions to become gel-like. |