Articles selected by Faculty of 1000: microRNA-target interactions; hominid gene control regions; pre-mRNA splicing; gene silencing during pathogenesis; multiple use of microarrays

microRNA-target interactions

Architecture of a validated microRNA::target interaction. Vella MC, Reinert K, Slack FJ. Chem Biol 2004, 11:1619-1623.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2005-6-3-314.asp#Vella webcite

Hominid gene control regions

Evidence for widespread degradation of gene control regions in hominid genomes. Keightley PD, Lercher MJ, Eyre-Walker A. PLoS Biol 2005, 3:e42.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2005-6-3-314.asp#Keightley webcite

Pre-mRNA splicing

Small molecule control of pre-mRNA splicing. Graveley BR. RNA 2005, January 20.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2005-6-3-314.asp#Graveley webcite

Gene silencing during pathogenesis

Trypanosoma brucei RNA interference in the mammalian host. Lecordier L, Walgraffe D, Devaux S, Poelvoorde P, Pays E, Vanhamme L. Mol Biochem Parasitol 2005, 142:127-131.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2005-6-3-314.asp#Lecordier webcite

Multiple use of microarrays

Simultaneous genotyping, gene-expression measurement, and detection of allele-specific expression with oligonucleotide arrays. Ronald J, Akey JM, Whittle J, Smith EN, Yvert G, Kruglyak L. Genome Res 2005, 15:284-291.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2005-6-3-314.asp#Ronald webcite

Genome Biologypaper reports
Genome Biology aims to highlight significant research articles newly published in other journals. From 2003, individual paper reports have been replaced by summaries of articles of interest to Genome Biology readers, taken from those highlighted by Faculty of 1000, a new online literature awareness tool published by BioMed Central. Faculty of 1000 systematically and comprehensively reviews the most interesting recent articles published in the biological sciences on the basis of recommendations of a faculty of over 1,400 selected leading researchers.

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