Table 2

Ranking of the 10 most negative and 10 most positive residual values in S. cerevisiae, S. pombe and C. albicans contexts

S. cerevisiae

S. pombe

C. albicans


Context
Residual
Context
Residual
Context
Residual

Most negative values
UUU → AAG
-24.58
GAA → CCU
-24.159
UUU → CCA
-32.691
GAU → AAG
-22.487
GAU → AAG
-24.124
UUC → GAA
-31.586
AUU → AAA
-21.546
UUU → AAG
-23.899
UCA → GAU
-28.317
AUU → AAG
-21.285
AUU → AAA
-22.923
AUU → AAG
-28.284
CUU → AAA
-20.656
UCU → AAG
-22.334
GGU → UUU
-27.198
UUU → AAA
-20.563
CUU → AAA
-21.25
AAC → UUA
-26.198
UCC → GAA
-20.069
GUU → AAA
-21.218
GAC → UUA
-25.795
AAG → UCU
-19.706
AUU → AAG
-21.08
UUU → AAG
-25.316
GAU → CAA
-19.274
UUU → AAA
-20.704
GGA → AAA
-25.26
GAA → CCA
-19.155
GAA → UCU
-20.698
UUC → GAU
-24.822






Most positive values
GAU → GAU
29.839
CAG → CAA
25.279
ACA → ACA
49.476
AAG → AAG
29.937
GAA → GAG
25.644
CAC → CAC
49.511
UUG → AAA
30.459
AAG → AAG
26.901
CCA → CCA
52.889
GAA → GAA
30.573
CUU → CGU
27.013
GAA → GAA
57.356
AAG → AAA
31.427
GAA → GAA
28.051
AAG → AAA
58.605
CAG → CAA
33.445
AGA → AGA
29.623
GCU → GCU
62.611
AGA → AGA
33.798
AAA → AAG
30.358
ACC → ACC
70.117
GGU → GGU
35.979
GCU → GCU
32.158
GGU → GGU
72.48
GCU → GCU
36.231
GGU → GGU
33.681
AAC → AAC
87.115
CAG → CAG
45.422
UCU → UCU
35.086
CAA → CAA
105.216

Anaconda was used to analyze the codon context of the complete genomes of S. cerevisiae, S. pombe and C. albicans. All possible codon contexts were ranked according to their calculated adjusted residuals, and the 10 most negative and 10 most positive were selected as extreme examples. The results indicate that only a small number of bad or good codon pairs (shown in bold) are shared between all three yeast species.

Moura et al. Genome Biology 2005 6:R28   doi:10.1186/gb-2005-6-3-r28