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The Adult Mouse Anatomical Dictionary: a tool for annotating and integrating data

Terry F Hayamizu1, Mary Mangan12, John P Corradi13, James A Kadin1 and Martin Ringwald1*

Author Affiliations

1 The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA

2 Current address: OpenHelix, 65 Main Street, Somerville, MA 02145, USA

3 Bristol-Myers Squibb Pharmaceutical Research Institute, 5 Research Parkway, Wallingford, CT 06492, USA

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Genome Biology 2005, 6:R29  doi:10.1186/gb-2005-6-3-r29

Published: 15 February 2005

Abstract

We have developed an ontology to provide standardized nomenclature for anatomical terms in the postnatal mouse. The Adult Mouse Anatomical Dictionary is structured as a directed acyclic graph, and is organized hierarchically both spatially and functionally. The ontology will be used to annotate and integrate different types of data pertinent to anatomy, such as gene expression patterns and phenotype information, which will contribute to an integrated description of biological phenomena in the mouse.