Genome Biology

official impact factor 6.89

A non-random walk through the genome

Brian Oliver* and Tom Misteli

Genome Biology 2005, 6:214 doi:10.1186/gb-2005-6-4-214

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Research article   Open Access

U3 snoRNA genes are multi-copy and frequently linked to U5 snRNA genes in Euglena gracilis§

J Michael Charette, Michael W Gray BMC Genomics 2009, 10:528 (16 November 2009)

Research article   Open Access

Coordinated evolution of co-expressed gene clusters in the Drosophila transcriptome

Jason G Mezey, Sergey V Nuzhdin, Fangfei Ye, Corbin D Jones BMC Evolutionary Biology 2008, 8:2 (7 January 2008)

Research article   Open Access

Phylogenomic analyses of KCNA gene clusters in vertebrates: why do gene clusters stay intact?

Simone Hoegg, Axel Meyer BMC Evolutionary Biology 2007, 7:139 (15 August 2007)

Surprisingly few regulatory elements have been retained in vertebrate KCNA gene clusters, which encode potassium channels, suggesting that processes other than regulatory evolution have led to the conservation of the gene clusters.

Research article   Open Access Highly Accessed

Motion as a phenotype: the use of live-cell imaging and machine visual screening to characterize transcription-dependent chromosome dynamics

David A Drubin, Arman M Garakani, Pamela A Silver BMC Cell Biology 2006, 7:19 (24 April 2006)

Live-cell imaging in yeast of the galactose-inducible GAL locus shows that upon transcriptional activation the GAL locus moves to the nuclear periphery, a process involving the mRNA export factor Sac3.

Research   Open Access Highly Accessed

Molecular processes during fat cell development revealed by gene expression profiling and functional annotation

Hubert Hackl, Thomas Burkard, Alexander Sturn, Renee Rubio, Alexander Schleiffer, Sun Tian, John Quackenbush, Frank Eisenhaber, Zlatko Trajanoski Genome Biology 2005, 6:R108 (19 December 2005)

In-depth bioinformatics analyses of expressed sequence tags found to be differentially expressed during differentiation of 3T3-L1 pre-adipocyte cells were combined with de novo functional annotation and mapping onto known pathways to generate a molecular atlas of fat-cell development.