A non-random walk through the genome
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* Corresponding author: Brian Oliver oliver@helix.nih.gov
1 National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
2 National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Genome Biology 2005, 6:214 doi:10.1186/gb-2005-6-4-214
Published: 31 March 2005Abstract
Recent publications on a wide range of eukaryotes indicate that genes showing particular expression patterns are not randomly distributed in the genome but are clustered into contiguous regions that we call neighborhoods. It seems probable that this organization is related to chromatin and the structure of the nucleus.