Genome Biology
Volume 6
Issue 4 |
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ReviewA non-random walk through the genomeBrian Oliver1  and Tom Misteli2  1National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA 2National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA  author email corresponding author email
Genome Biology 2005,
6:214doi:10.1186/gb-2005-6-4-214
Subject areas: Molecular biology, Cell biology, Genome studies, Genetics Abstract
Recent publications on a wide range of eukaryotes indicate that genes showing particular expression patterns are not randomly distributed in the genome but are clustered into contiguous regions that we call neighborhoods. It seems probable that this organization is related to chromatin and the structure of the nucleus. | 
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