Genome Biology

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Contribution of transcriptional regulation to natural variations in Arabidopsis

Wenqiong J Chen, Sherman H Chang, Matthew E Hudson, Wai-King Kwan, Jingqiu Li, Bram Estes, Daniel Knoll, Liang Shi and Tong Zhu*

Genome Biology 2005, 6:R32 doi:10.1186/gb-2005-6-4-r32

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Promoter architecture and the evolvability of gene expression

Itay Tirosh, Naama Barkai, Kevin J Verstrepen Journal of Biology 2009, 8:95 (14 December 2009)

Major evolutionary change depends on changes in gene expression. Itay Tirosh and colleagues review recent research on the influence of promoter architecture and mutations in regulatory proteins on divergent expression patterns and suggest what is required for evolvability.