Genome Biology

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The microbial selenoproteome of the Sargasso Sea

Yan Zhang, Dmitri E Fomenko and Vadim N Gladyshev*

Genome Biology 2005, 6:R37 doi:10.1186/gb-2005-6-4-r37

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Research article   Open Access

Abundance and functional diversity of riboswitches in microbial communities

Marat D Kazanov, Alexey G Vitreschak, Mikhail S Gelfand BMC Genomics 2007, 8:347 (1 October 2007)

Research   Open Access

Dynamic evolution of selenocysteine utilization in bacteria: a balance between selenoprotein loss and evolution of selenocysteine from redox active cysteine residues

Yan Zhang, Hector Romero, Gustavo Salinas, Vadim N Gladyshev Genome Biology 2006, 7:R94 (20 October 2006)

Comparative genomics and evolutionary analyses to examine the dynamics of selenocysteine utilization in bacteria reveal a dynamic balance between selenoprotein origin and loss.

Method   Open Access

A computational method to predict genetically encoded rare amino acids in proteins

Barnali N Chaudhuri, Todd O Yeates Genome Biology 2005, 6:R79 (31 August 2005)

A new method for predicting recoding by rare amino acids such as selenocysteine and pyrrolysine was used to survey a set of microbial genomes.

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Metagenomics for studying unculturable microorganisms: cutting the Gordian knot

Patrick D Schloss, Jo Handelsman Genome Biology 2005, 6:229 (1 August 2005)

Recent advances in shotgun sequencing and computational methods for genome assembly have advanced the field of metagenomics, the culture-independent cloning and analysis of microbial DNA extracted directly from an environmental sample, to provide glimpses into the life of uncultured microorganisms.

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Making sense of nonsense: the evolution of selenocysteine usage in proteins

Paul R Copeland Genome Biology 2005, 6:221 (27 May 2005)

A recent analysis of sequences derived from organisms in the Sargasso Sea has revealed a surprisingly different set of selenium-containing proteins than that previously found in sequenced genomes.