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Selenoprotein families identified in the Sargasso Sea database |
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| Prokaryotic selenoprotein family |
Unique sequences |
COG/Pfam ID |
COG/Pfam description |
|
|
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| Known selenoproteins (209 sequences) |
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| SelW-like protein |
48 |
Pfam05169 |
Selenoprotein W-related |
| Peroxiredoxin (Prx) |
43 |
COG1225 |
Peroxiredoxin |
| Proline reductase (PrdB) |
42 |
- |
|
| Selenophosphate synthetase |
28 |
COG0709 |
Selenophosphate synthetase |
| Prx-like protein |
22 |
COG0450 |
Peroxiredoxin-like |
| Thioredoxin (Trx) |
11 |
COG3118 |
Thioredoxin |
| Formate dehydrogenase alpha chain (fdhA) |
8 |
COG0243 |
Anaerobic dehydrogenases |
| Glutathione peroxidase (GPx) |
5 |
COG0386 |
Glutathione peroxidase |
| Glycine reductase selenoprotein A (grdA) |
1 |
- |
|
| Glycine reductase selenoprotein B (grdB) |
1 |
Pfam07355 |
Glycine reductase selenoprotein B |
| New selenoproteins (101 sequences) |
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| AhpD-like protein |
27 |
COG2128 |
Uncharacterized conserved protein |
| Arsenate reductase |
14 |
COG1393 |
Arsenate reductase and related proteins |
| Molybdopterin biosynthesis MoeB protein |
11 |
COG0476 |
Dinucleotide-utilizing enzymes, molybdopterin biosynthesis |
| Glutaredoxin (Grx) |
10 |
COG0695 |
Glutaredoxin and related proteins |
| DsbA-like protein |
9 |
COG2761 |
DsbA-like |
| Glutathione S-transferase |
4 |
COG0625 |
Glutathione S-transferase |
| Deiodinase-like protein |
4 |
Pfam00837 |
Iodothyronine deiodinase |
| Thiol-disulfide isomerase-like protein |
4 |
- |
|
| CMD domain-containing protein |
4 |
Pfam02627 |
Carboxymuconolactone decarboxylase |
| Hypothetical protein 1 |
4 |
- |
|
| Rhodanese-related sulfurtransferase |
3 |
COG2897 |
Rhodanese-related sulfurtransferase |
| OsmC-like protein |
3 |
COG1765 |
Predicted redox protein, OsmC-like |
| DsrE-like protein |
2 |
Pfam02635 |
DsrE-like |
| DsbG-like protein |
1 |
COG1651 |
DsbG, Protein-disulfide isomerase |
| NADH:ubiquinone oxidoreductase |
1 |
COG2209 |
NADH:ubiquinone oxidoreductase |
| Total |
310 |
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Classification of selenoproteins (10 previously known and 15 new prokaryotic selenoprotein families) is supported by COG or Pfam sequence clusters (or both) as shown in this table. The number of individual selenoprotein sequences for each family is indicated. | |||
Zhang et al. Genome Biology 2005 6:R37 doi:10.1186/gb-2005-6-4-r37 |
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