Table 1 |
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|
Genetic interactions of mutant genes with biological processes |
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|
Gene |
Form* |
Interaction |
Biological process |
-log10P |
|
|
||||
|
PBS2 |
null |
Additive |
Signal transduction |
2.99 |
|
PBS2 |
null |
Additive |
Small gtpase mediated signal transduction |
2.96 |
|
STE12 |
gf |
Single-nonmonotonic to |
Protein targeting |
2.87 |
|
STE11 |
da |
Noninteractive |
Cell cycle |
2.73 |
|
PHD1 |
gf |
Hypostatic to |
Invasive growth |
2.68 |
|
PDE2 |
null |
Noninteractive |
Protein amino acid phosphorylation |
2.56 |
|
HSL1 |
null |
Suppressed by |
Cell wall organization and biogenesis |
2.52 |
|
STE20 |
gf |
Single-nonmonotonic to |
Protein targeting |
2.31 |
|
EGT2 |
null |
Conditioned by |
Invasive growth |
2.30 |
|
ISW1 |
null |
Suppresses |
Small gtpase mediated signal transduction |
2.30 |
|
CLB1 |
null |
Noninteractive |
Protein metabolism |
2.30 |
|
STE11 |
da |
Suppresses |
Cell surface receptor linked signal transduction |
2.28 |
|
BEM1 |
gf |
Conditioned by |
Nucleobase, nucleoside, nucleotide and nucleic acid metabolism |
2.25 |
|
PBS2 |
null |
Additive |
Ras protein signal transduction |
2.24 |
|
PBS2 |
null |
Additive |
Sporulation |
2.24 |
|
TEC1 |
gf |
Synthetic |
Intracellular signaling cascade |
2.19 |
|
IPK1 |
null |
Additive |
M phase |
1.95 |
|
TEC1 |
null |
Epistatic to |
Metabolism |
1.94 |
|
TEC1 |
gf |
Conditioned by |
Carbohydrate metabolism |
1.94 |
|
TEC1 |
gf |
Conditioned by |
Ras protein signal transduction |
1.94 |
|
BUD4 |
null |
Noninteractive |
Establishment of cell polarity |
1.94 |
|
HMS1 |
null |
Noninteractive |
Protein amino acid phosphorylation |
1.83 |
|
YGR045C |
null |
Noninteractive |
Protein amino acid phosphorylation |
1.83 |
|
|
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|
*gf, gain-of-function; da, dominant-active. |
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|
Drees et al. Genome Biology 2005 6:R38 doi:10.1186/gb-2005-6-4-r38 |
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