Table 1

Genetic interactions of mutant genes with biological processes

Gene

Form*

Interaction

Biological process

-log10P


PBS2

null

Additive

Signal transduction

2.99

PBS2

null

Additive

Small gtpase mediated signal transduction

2.96

STE12

gf

Single-nonmonotonic to

Protein targeting

2.87

STE11

da

Noninteractive

Cell cycle

2.73

PHD1

gf

Hypostatic to

Invasive growth

2.68

PDE2

null

Noninteractive

Protein amino acid phosphorylation

2.56

HSL1

null

Suppressed by

Cell wall organization and biogenesis

2.52

STE20

gf

Single-nonmonotonic to

Protein targeting

2.31

EGT2

null

Conditioned by

Invasive growth

2.30

ISW1

null

Suppresses

Small gtpase mediated signal transduction

2.30

CLB1

null

Noninteractive

Protein metabolism

2.30

STE11

da

Suppresses

Cell surface receptor linked signal transduction

2.28

BEM1

gf

Conditioned by

Nucleobase, nucleoside, nucleotide and nucleic acid metabolism

2.25

PBS2

null

Additive

Ras protein signal transduction

2.24

PBS2

null

Additive

Sporulation

2.24

TEC1

gf

Synthetic

Intracellular signaling cascade

2.19

IPK1

null

Additive

M phase

1.95

TEC1

null

Epistatic to

Metabolism

1.94

TEC1

gf

Conditioned by

Carbohydrate metabolism

1.94

TEC1

gf

Conditioned by

Ras protein signal transduction

1.94

BUD4

null

Noninteractive

Establishment of cell polarity

1.94

HMS1

null

Noninteractive

Protein amino acid phosphorylation

1.83

YGR045C

null

Noninteractive

Protein amino acid phosphorylation

1.83


*gf, gain-of-function; da, dominant-active.

Drees et al. Genome Biology 2005 6:R38   doi:10.1186/gb-2005-6-4-r38

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