Table 1

Genetic interactions of mutant genes with biological processes

Gene
Form*
Interaction
Biological process
-log10P

PBS2
null
Additive
Signal transduction
2.99
PBS2
null
Additive
Small gtpase mediated signal transduction
2.96
STE12
gf
Single-nonmonotonic to
Protein targeting
2.87
STE11
da
Noninteractive
Cell cycle
2.73
PHD1
gf
Hypostatic to
Invasive growth
2.68
PDE2
null
Noninteractive
Protein amino acid phosphorylation
2.56
HSL1
null
Suppressed by
Cell wall organization and biogenesis
2.52
STE20
gf
Single-nonmonotonic to
Protein targeting
2.31
EGT2
null
Conditioned by
Invasive growth
2.30
ISW1
null
Suppresses
Small gtpase mediated signal transduction
2.30
CLB1
null
Noninteractive
Protein metabolism
2.30
STE11
da
Suppresses
Cell surface receptor linked signal transduction
2.28
BEM1
gf
Conditioned by
Nucleobase, nucleoside, nucleotide and nucleic acid metabolism
2.25
PBS2
null
Additive
Ras protein signal transduction
2.24
PBS2
null
Additive
Sporulation
2.24
TEC1
gf
Synthetic
Intracellular signaling cascade
2.19
IPK1
null
Additive
M phase
1.95
TEC1
null
Epistatic to
Metabolism
1.94
TEC1
gf
Conditioned by
Carbohydrate metabolism
1.94
TEC1
gf
Conditioned by
Ras protein signal transduction
1.94
BUD4
null
Noninteractive
Establishment of cell polarity
1.94
HMS1
null
Noninteractive
Protein amino acid phosphorylation
1.83
YGR045C
null
Noninteractive
Protein amino acid phosphorylation
1.83

*gf, gain-of-function; da, dominant-active.

Drees et al. Genome Biology 2005 6:R38   doi:10.1186/gb-2005-6-4-r38