Genome Biology

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Consolidating the set of known human protein-protein interactions in preparation for large-scale mapping of the human interactome

Arun K Ramani1, Razvan C Bunescu2, Raymond J Mooney2* and Edward M Marcotte3,1*

Author Affiliations

1 Center for Systems and Synthetic Biology and Institute for Cellular and Molecular Biology, University of Texas, Austin, TX 78712, USA

2 Department of Computer Sciences, University of Texas, Austin, TX 78712, USA

3 Department of Chemistry and Biochemistry, University of Texas, Austin, TX 78712, USA

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Genome Biology 2005, 6:R40 doi:10.1186/gb-2005-6-5-r40

Published: 15 April 2005

Additional files

Additional File 1:

Training set of 200 Medline abstracts with all occurrences of protein names tagged

Format: GZ Size: 111KB Download file

Open Data

Additional File 2:

Training set of 750 Medline abstracts with all occurrences of protein names tagged

Format: GZ Size: 434KB Download file

Open Data

Additional File 3:

Dictionary of human protein names and synonyms indexed to LocusLink identifiers

Format: TXT Size: 2.9MB Download file

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Additional File 4:

Final set of 31,609 protein interactions between 7,748 proteins derived from this analysis

Format: TXT Size: 943KB Download file

Open Data

Additional File 5:

Final set of co-citation/Bayesian classifier-derived interactions with the PubMed identifiers of co-citing abstracts

Format: TXT Size: 812KB Download file

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Additional File 6:

Benchmark training set of functional annotations

Format: TXT Size: 102KB Download file

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Additional File 7:

Benchmark test set of functional annotations

Format: TXT Size: 102KB Download file

Open Data

Additional File 8:

Benchmark set of physical interactions

Format: TXT Size: 248KB Download file

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Additional File 9:

Discriminating word list used by the Bayesian classifier to estimate the likelihood of Medline abstracts to discuss protein interactions

Format: TXT Size: 2KB Download file

Open Data