Table 1

The initial list of the interactions and proteins represented in each of the existing human protein interaction datasets with total interactions, unique self-interactions and unique non-self interactions

Dataset
Version
Total interactions (number of proteins)
Unique self (A-A) interactions (number of proteins)
Unique (A-B) interactions (number of proteins)

Reactome
08/03/04
12,497 (6,257)
160 (160)
12,336 (807)
BIND
08/03/04
6,212 (5,412)
549 (549)
5,663 (4,762)
HPRD*
04/12/04
12,013 (4,122)
3,028 (3,028)
6,054 (2,747)
Orthology transfer (all)
03/31/04
71,497 (6,257)
373 (373)
71,124 (6,228)
Orthology transfer (core)
03/31/04
11,488 (3,918)
206 (206)
11,282 (3,863)

*Difficult to measure: HPRD records genes by their names, leading occasionally to entries for the same gene under different synonyms. The numbers reported are after mapping to LocusLink.

Ramani et al. Genome Biology 2005 6:R40   doi:10.1186/gb-2005-6-5-r40