Minireview
Making sense of nonsense: the evolution of selenocysteine usage in proteins
Department of Molecular Genetics, Microbiology and Immunology, UMDNJ-Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA
Genome Biology 2005, 6:221 doi:10.1186/gb-2005-6-6-221
Published: 27 May 2005Abstract
A recent analysis of sequences derived from organisms in the Sargasso Sea has revealed a surprisingly different set of selenium-containing proteins than that previously found in sequenced genomes and suggests that selenocysteine utilization has been lost by many groups of organisms during evolution.
