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Identification of co-regulated transcripts affecting male body size in Drosophila

Cynthia J Coffman, Marta L Wayne, Sergey V Nuzhdin, Laura A Higgins and Lauren M McIntyre*

Genome Biology 2005, 6:R53 doi:10.1186/gb-2005-6-6-r53

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Natural genetic variation in transcriptome reflects network structure inferred with major effect mutations: insulin/TOR and associated phenotypes in Drosophila melanogaster

Sergey V Nuzhdin, Jennifer A Brisson, Andrew Pickering, Marta L Wayne, Lawrence G Harshman, Lauren M McIntyre BMC Genomics 2009, 10:124 (24 March 2009)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Naturally-occurring variation in Drosophila insulin/TOR signaling pathway genes affects expression and phenotypes similarly to gene knockouts, but the sparse picture of regulatory networks derived from knockout studies on inbred lines is probably oversimplified.

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Sex-specific expression of alternative transcripts in Drosophila

Lauren M McIntyre, Lisa M Bono, Anne Genissel, Rick Westerman, Damion Junk, Marina Telonis-Scott, Larry Harshman, Marta L Wayne, Artyom Kopp, Sergey V Nuzhdin Genome Biology 2006, 7:R79 (25 August 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A genome-wide microarray analysis of sex-specific expression of alternative transcripts in Drosophila shows sexual dimorphism in transcript abundance for 53% of the genes.

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