Figure 6.

Alignment of FT and GGT1 beta subunits (FTb, GGT1b) in the regions of binding-pocket residues (marked with arrow) using ClustalX [57]. Residue ranges shown above and below correspond to the numbering in the PDB structures of rat FT beta (PDB 1D8D) and GGT1 beta (PDB 1N4Q), respectively. Accession numbers are as follows (GenBank unless indicated otherwise): Hs (Homo sapiens) FTb, NP_002019; GGT1b, NP_005014; Mm (Mus musculus) NP_666039; NP_766215; Rn (Rattus norvegicus) PDB 1D8D; 1N4Q; Tn (Tetraodon nigroviridis) CAG09215; CAF904630; Dm (Drosophila melanogaster) NP_650540; NP_525100; Ag (Anopheles gambiae) XP_321357; XP_317045; Ce (Caenorhabditis elegans) NP_506580; NP_496848; At (Arabidopsis thaliana) NP_198844; NP_181487; Sp (Schizosaccharomyces pombe) NP_594251; NP_594142; Sc (Saccharomyces cerevisiae) P22007; NP_011360. Standard ClustalX coloring (according to conserved amino acid type).