Genome Biology

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Open Access

Creation and disruption of protein features by alternative splicing - a novel mechanism to modulate function

Michael Hiller, Klaus Huse, Matthias Platzer and Rolf Backofen*

Genome Biology 2005, 6:R58 doi:10.1186/gb-2005-6-7-r58

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Research   Open Access

Phylogenetically widespread alternative splicing at unusual GYNGYN donors

Michael Hiller, Klaus Huse, Karol Szafranski, Philip Rosenstiel, Stefan Schreiber, Rolf Backofen, Matthias Platzer Genome Biology 2006, 7:R65 (25 July 2006)

Computational and experimental evidence is given for alternative splicing at the unusual GYNGYN motif in several species, enabling in most cases subtle protein variations.

Research article   Open Access

Identification and evolutionary analysis of novel exons and alternative splicing events using cross-species EST-to-genome comparisons in human, mouse and rat

Feng-Chi Chen, Chuang-Jong Chen, Jar-Yi Ho, Trees-Juen Chuang BMC Bioinformatics 2006, 7:136 (15 March 2006)