Table 3 |
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|
Nineteen candidate genes with cis-eQTL in chromosome 19 locus |
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|
cis-QTL gene symbol |
Physical location of the gene (Mb) |
Estimated physical location of the eQTL (Mb) |
Correlation with subcutaneous fat mass |
|
|
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|
RIKEN cDNA 9530025L08 |
29.5 |
48.6 |
-0.29* |
|
Cyp2c40† |
39.1 |
40.6 |
0.24 |
|
Col17a1 |
47.0 |
40.6 |
-0.25* |
|
Scd2 |
43.6 |
40.6 |
-0.19 |
|
Slk |
46.9 |
41.8 |
-0.07 |
|
Cyp2c37 |
39.3 |
37.0 |
0.32* |
|
Cyp2c39† |
38.8 |
40.6 |
0.03 |
|
Gsto1 |
47.2 |
41.8 |
0.26* |
|
Rnf134 |
46.4 |
48.6 |
0.05 |
|
Cutc |
43.1 |
39.4 |
0.25* |
|
Cpn1 |
43.3 |
39.4 |
0.28* |
|
Cnnm1 |
42.8 |
46.2 |
0.27* |
|
Acsl5 |
54.6 |
37.0 |
0.30* |
|
RIKEN cDNA 1810018P12 |
32.0 |
35.7 |
0.24 |
|
Pik3ap1 |
40.6 |
39.4 |
-0.07 |
|
RIKEN cDNA 0610010D20 |
41.4 |
41.8 |
0.10 |
|
RIKEN cDNA 4833409A17 |
42.1 |
40.6 |
-0.21 |
|
RIKEN cDNA 4930538D17 |
45.7 |
38.2 |
-0.22 |
|
RIKEN cDNA 5730455O13 |
37.4 |
40.6 |
0.14 |
|
|
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*Significant correlation of transcript levels with subcutaneous fat mass (p < 0.05). †The two genes that solely contributed to the significant LOD score of the fatty-acid metabolism and γ-hexachlorocyclohexane degredation principal components to chromosome 19 (see text for details). |
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Ghazalpour et al. Genome Biology 2005 6:R59 doi:10.1186/gb-2005-6-7-r59 |
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