Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human
1 Illumigen Biosciences Inc., Suite 450, 2203 Airport Way South, Seattle, WA 98134, USA
2 Department of Microbiology, University of Washington, Seattle, WA 98195-8070, USA
3 Washington National Primate Research Center, University of Washington, Seattle, WA 98195-8070, USA
Genome Biology 2005, 6:R60 doi:10.1186/gb-2005-6-7-r60Published: 30 June 2005
We report the initial sequencing and comparative analysis of the Macaca mulatta transcriptome. Cloned sequences from 11 tissues, nine animals, and three species (M. mulatta, M. fascicularis, and M. nemestrina) were sampled, resulting in the generation of 48,642 sequence reads. These data represent an initial sampling of the putative rhesus orthologs for 6,216 human genes. Mean nucleotide diversity within M. mulatta and sequence divergence among M. fascicularis, M. nemestrina, and M. mulatta are also reported.