Table 5

Interspecies substitution rates

Gene
Alignment length
Number of reads
Frequency per kilobase






M f.
M.m.
M.n.
m vs n*
m vs f*
n vs f*

ADH1B
819
8
5
14
0.00
0.00
2.44
AFP
537
1
3
1
11.17
7.45
3.72
ALB
2047
> 20
> 20
> 20
0.00
0.49
0.49
AMBP
731
1
5
4
4.10
1.37
5.47
ANGPTL3
371
1
1
2
2.70
0.00
2.70
APOA1
746
10
76
2
10.72
4.02
5.36
APOA2
431
3
4
5
6.96
4.64
2.32
APOC4
312
3
1
1
16.03
12.82
16.03
APOE
217
2
2
2
4.61
4.61
0.00
APOH
1007
4
14
14
2.98
0.00
2.98
B2M
587
1
90
1
0.00
11.93
11.93
EEF1A1
920
7
>20
7
0.00
0.00
0.00
FGA
379
3
6
1
7.92
0.00
7.92
FGB
407
3
43
11
2.46
0.00
2.46
FGG
694
3
24
9
1.44
1.44
2.88
HPR
567
2
20
12
3.53
1.76
1.76
RPL9
680
1
35
1
4.41
4.41
0.00
SERPINC1
787
1
3
1
1.27
2.54
1.27
TTR
599
5
2
6
5.01
3.34
5.01
UBC
460
1
40
1
0.00
0.00
0.00
UGT2B7
228
1
13
1
8.77
0.00
8.77




Mean
5.88
3.80
5.22




Median
3.53
1.44
2.70




SD
4.38
3.80
4.19

*Pair wise interspecies substitution frequencies computed on a gene-by-gene basis M.f., Macaca fascicularis; M.m., M. mulatta; M.n., M. nemestrina.

Magness et al. Genome Biology 2005 6:R60   doi:10.1186/gb-2005-6-7-r60