The SET-domain protein superfamily: protein lysine methyltransferases
1 Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
2 Department of Biochemistry, Emory University School of Medicine, 1510 Clifton Road, Atlanta, Georgia 30322, USA
3 Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109-0606, USA
Genome Biology 2005, 6:227 doi:10.1186/gb-2005-6-8-227Published: 2 August 2005
The SET-domain protein methyltransferase superfamily includes all but one of the proteins known to methylate histones on lysine. Histone methylation is important in the regulation of chromatin and gene expression.