Table 4 |
|||||
|
Biological process downregulated in vitro |
|||||
|
GO category |
Total number of genes |
Genes changed |
Log10 (p-value) |
FDR |
ID |
|
|
|||||
|
Membrane signaling and cell adhesion |
|||||
|
Cell communication |
1088 |
565 |
-13.76 |
0.0000 |
GO:0007154 |
|
Signal transduction |
831 |
428 |
-8.86 |
0.0000 |
GO:0007165 |
|
Cell surface receptor linked signal transduction |
413 |
232 |
-8.66 |
0.0000 |
GO:0007166 |
|
Cell adhesion |
257 |
139 |
-4.10 |
0.0000 |
GO:0007155 |
|
Cell-cell signaling |
240 |
132 |
-4.38 |
0.0000 |
GO:0007267 |
|
Cell motility |
197 |
105 |
-2.91 |
0.0171 |
GO:0006928 |
|
G-protein coupled receptor protein signaling pathway |
175 |
102 |
-4.87 |
0.0000 |
GO:0007186 |
|
Enzyme linked receptor protein signaling pathway |
107 |
61 |
-2.78 |
0.0231 |
GO:0007167 |
|
Cell-cell adhesion |
87 |
53 |
-3.41 |
0.0000 |
GO:0016337 |
|
G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) |
35 |
23 |
-2.32 |
0.0490 |
GO:0007200 |
|
Extracellular structure organization and biogenesis |
17 |
14 |
-3.02 |
0.0029 |
GO:0043062 |
|
Extracellular matrix organization and biogenesis |
16 |
13 |
-2.73 |
0.0225 |
GO:0030198 |
|
|
|||||
|
Sandberg and Ernberg Genome Biology 2005 6:R65 doi:10.1186/gb-2005-6-8-r65 |
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