Genome Biology
Volume 6
Issue 8 |
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  MethodGenome-wide promoter extraction and analysis in human, mouse, and rat author email corresponding author email
Genome Biology 2005,
6:R72doi:10.1186/gb-2005-6-8-r72
Subject areas: Bioinformatics, Genome studies, Molecular biology Abstract
Large-scale and high-throughput genomics research needs reliable and comprehensive genome-wide promoter annotation resources. We have conducted a systematic investigation on how to improve mammalian promoter prediction by incorporating both transcript and conservation information. This enabled us to build a better multispecies promoter annotation pipeline and hence to create CSHLmpd (Cold Spring Harbor Laboratory Mammalian Promoter Database) for the biomedical research community, which can act as a starting reference system for more refined functional annotations. | 
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