Schematic of two-step model. In order to successfully classify the sarcoma with the minimum of errors a two-step approach was used. A mixture of single sarcoma and composite classes were used for prediction in step one. Then, in step two, composite classes were separated into their constituent tumors. * The SPIN (spindle-like) group comprising PMS, LMS, and DCS could not be separated by our model. ** The WLS and LMA could not be separated by our model but were distinct from MLS. ADIP, adipocytic tumors; RHAB, rhabdomyosarcoma.
Henderson et al. Genome Biology 2005 6:R76 doi:10.1186/gb-2005-6-9-r76