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Opinion

On the evolution of the standard amino-acid alphabet

Yi Lu and Stephen Freeland email

Department of Biological Sciences, University of Maryland, Baltimore County, Baltimore, MD 21250, USA

author email corresponding author email

Genome Biology 2006, 7:102doi:10.1186/gb-2006-7-1-102

Published: 1 February 2006

Subject areas: Evolution, Molecular biology, Biochemistry and structural biology

Abstract

Although one standard amino-acid 'alphabet' is used by most organisms on Earth, the evolutionary cause(s) and significance of this alphabet remain elusive. Fresh insights into the origin of the alphabet are now emerging from disciplines as diverse as astrobiology, biochemical engineering and bioinformatics.


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