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Highly Accessed Review

Attacking pathogens through their hosts

Paul Kellam

Author Affiliations

Virus Genomics and Bioinformatics Group, Division of Infection and Immunity, University College London, London W1T 4JF, UK

Genome Biology 2006, 7:201  doi:10.1186/gb-2006-7-1-201

Published: 30 January 2006

Abstract

Through understanding the intricacies of host-pathogen interactions, it is now possible to inhibit the growth of microbes, especially viruses, by targeting host-cell proteins and functions. This new antimicrobial strategy has proved effective in the laboratory and in the clinic, and it has great potential for the future.