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Functional genomics of early cortex patterning

David Chambers1* and Gord Fishell2

Author Affiliations

1 Wellcome Trust Functional Genomics Development Initiative, MRC Centre for Developmental Neurobiology, King's College London, Guy's Campus, London SE1 1UL, UK

2 Developmental Genetics Program and the Department of Cell Biology, Skirball Institute of Biomolecular Medicine, New York University Medical Center, 550 First Avenue, New York, NY 10016, USA

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Genome Biology 2006, 7:202  doi:10.1186/gb-2006-7-1-202

Published: 31 January 2006

Abstract

Several lines of evidence have illuminated the fundamental developmental principles involved in establishing and implementing pattern formation in the mammalian neocortex. A recent study has sought to unravel the underlying genetic control of cortex patterning by elucidating the transcriptional profile of discrete neocortical regions.