Functional genomics of early cortex patterning
1 Wellcome Trust Functional Genomics Development Initiative, MRC Centre for Developmental Neurobiology, King's College London, Guy's Campus, London SE1 1UL, UK
2 Developmental Genetics Program and the Department of Cell Biology, Skirball Institute of Biomolecular Medicine, New York University Medical Center, 550 First Avenue, New York, NY 10016, USA
Genome Biology 2006, 7:202 doi:10.1186/gb-2006-7-1-202Published: 31 January 2006
Several lines of evidence have illuminated the fundamental developmental principles involved in establishing and implementing pattern formation in the mammalian neocortex. A recent study has sought to unravel the underlying genetic control of cortex patterning by elucidating the transcriptional profile of discrete neocortical regions.