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Functional genomics of early cortex patterning

David Chambers1 email and Gord Fishell2

1Wellcome Trust Functional Genomics Development Initiative, MRC Centre for Developmental Neurobiology, King's College London, Guy's Campus, London SE1 1UL, UK

2Developmental Genetics Program and the Department of Cell Biology, Skirball Institute of Biomolecular Medicine, New York University Medical Center, 550 First Avenue, New York, NY 10016, USA

author email corresponding author email

Genome Biology 2006, 7:202doi:10.1186/gb-2006-7-1-202

Published: 31 January 2006

Subject areas: Development, Neurobiology, Genetics, Genome studies

Abstract

Several lines of evidence have illuminated the fundamental developmental principles involved in establishing and implementing pattern formation in the mammalian neocortex. A recent study has sought to unravel the underlying genetic control of cortex patterning by elucidating the transcriptional profile of discrete neocortical regions.


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