Table 1

Multiple exon alignment of the alternative exons of the cluster containing exon 6

Drosophila spp.


melanogaster

yakuba

ananassae

pseudoobscura

mojavensis

virilis


6.1

6.1

6.1

6.1

6.1

6.1

6.2

6.2

6.2

6.2

6.2

6.2

6.3

6.3

6.3

6.3

6.3

6.3

-

-

6.4

6.4

6.4

6.4

6.4

6.4

6.5

6.5

6.5

6.5

6.5

6.5

6.6

6.6

6.6

6.6

-

-

6.7

-

-

-

6.6

6.6

6.8

6.7

6.7

6.7

6.7

6.7

6.9

6.8

6.8

6.8

6.8

-

6.10

6.9

6.9

6.9

6.9

6.8

6.11

6.10

6.10

6.10

6.10

6.9

6.12

6.11

6.11

6.11

-

-

-

-

-

6.12

6.11*

6.10*

6.13

6.12

-

6.13

6.12

6.11

6.14

6.13

-

6.14

6.13

6.12

6.15

6.14

6.12

6.15

-

-

-

-

6.13

-

6.14

-

6.16

6.15

6.14

6.16

-

-

6.17

-

6.15

6.17

6.15

6.13

6.18

6.16

6.16

6.18

6.16

6.14

6.19

6.17

6.17

6.19

6.17

6.15

6.20

6.18

6.18

6.20

6.18

6.16

6.21

6.19

6.19

6.21

6.19

-

6.22

6.20

6.20

6.22

6.20

6.17

6.23

-

-

-

-

-

-

-

6.21

6.23

-

-

-

-

6.22

6.24

-

-

-

-

6.23

6.25

6.21

6.18

6.24

6.21

6.24

6.26

-

6.19

-

-

6.25

6.27

6.22

-

6.25

6.22

6.26

6.28

6.23

6.20

-

6.23

-

-

6.24

6.21

6.26

6.24

6.27

6.29

6.25

6.22

6.27

6.25

6.28

6.30

6.26

6.23

6.28

6.26

6.29

6.31

6.27

6.24

-

6.27

6.30

6.32

6.28

6.25

6.29

6.28

6.31

6.33

6.29

-

6.30

6.29

6.32

6.34

6.30

6.26

6.31

6.30

6.33

6.35

6.31

6.27

6.32

-

6.34

6.36

6.32

6.28

6.33

6.31

6.35

6.37

-

-

-

6.32

6.36

6.38

6.33

6.29

6.34

6.33

6.37

6.39

6.34

6.30

-

-

-

-

-

-

-

-

6.38

6.40

6.35

6.31

-

6.34

6.39

6.41

6.36

6.32

6.35

6.35

-

-

6.37

6.33

6.36

6.36

-

-

-

-

-

6.37

-

-

6.38

-

-

-

6.40

6.42

6.39

6.34

6.37

6.38

6.41

6.43

6.40

6.35

6.38

6.39

6.42

6.44

6.41

6.36*

6.39

6.40

6.43

6.45

6.42

-

6.40

6.41

6.44

6.46

6.43

6.37

6.41

6.42

-

-

6.44

6.38

-

6.43

6.45

6.47

6.45

6.39

6.42

6.44

6.46

6.48

6.46

6.40

6.43

6.45

6.47

6.49

6.47

6.41

6.44

6.46

6.48

6.50

6.48

6.42*

6.45

6.47

6.49

6.51

-

-

6.46

6.48

6.50

6.52


The rows contain sets of orthologous exons, and each column refers to the species (Drosophila melanogaster, D. yakuba, D. ananassae, D. pseudoobscura, D. mojavensis and D. virilis). Alignment was achieved by clustering together exons connected by neighboring branches in the phylogenetic tree shown in Additional data file 1. Exons labeled by an asterisk (such as exon 6.11 of D. melanogaster, which has neither a dot plot line in Figure 4 and no observed expression level in [12]) appear as isolated leaves in the phylogenetic tree, suggesting that they are probably nonfunctional and their sequences have randomly drifted by evolution.

Anastassiou et al. Genome Biology 2006 7:R2   doi:10.1186/gb-2006-7-1-r2

Open Data