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Systematic profiling of cellular phenotypes with spotted cell microarrays reveals mating-pheromone response genes

Rammohan Narayanaswamy†, Wei Niu†, Alexander D Scouras†, G Traver Hart, Jonathan Davies, Andrew D Ellington, Vishwanath R Iyer* and Edward M Marcotte*

Genome Biology 2006, 7:R6 doi:10.1186/gb-2006-7-1-r6

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Broad network-based predictability of Saccharomyces cerevisiae gene loss-of-function phenotypes

Kriston L McGary, Insuk Lee, Edward M Marcotte Genome Biology 2007, 8:R258 (5 December 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | Editor’s summary

Loss-of-function phenotypes of yeast genes can be predicted from the loss-of-function phenotypes of their neighbours in functional gene networks. This could potentially be applied to the prediction of human disease genes.

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