Genome Biology

official impact factor 6.89

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CellProfiler: image analysis software for identifying and quantifying cell phenotypes

Anne E Carpenter, Thouis R Jones, Michael R Lamprecht, Colin Clarke, In H Kang, Ola Friman, David A Guertin, Joo H Chang, Robert A Lindquist, Jason Moffat, Polina Golland and David M Sabatini*

Genome Biology 2006, 7:R100 doi:10.1186/gb-2006-7-10-r100

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BioMed Central: 12 citations

Methodology article   Open Access

Detailed interrogation of trypanosome cell biology via differential organelle staining and automated image analysis

Richard J Wheeler, Keith Gull, Eva Gluenz BMC Biology 2012, 10:1 (3 January 2012)

Research article   Open Access Highly Accessed

Cathepsin K deficiency in mice induces structural and metabolic changes in the central nervous system that are associated with learning and memory deficits

Stephanie Dauth, Ruxandra F Sîrbulescu, Silvia Jordans, Maren Rehders, Linda Avena, Julia Oswald, Alexander Lerchl, Paul Saftig, Klaudia Brix BMC Neuroscience 2011, 12:74 (27 July 2011)

Software   Open Access Highly Accessed

BioIMAX: A Web 2.0 approach for easy exploratory and collaborative access to multivariate bioimage data

Christian Loyek, Nasir M Rajpoot, Michael Khan, Tim W Nattkemper BMC Bioinformatics 2011, 12:297 (21 July 2011)

Software   Open Access

Gebiss: an ImageJ plugin for the specification of ground truth and the performance evaluation of 3D segmentation algorithms

Janos Kriston-Vizi, Ng Thong, Cheok Poh, Kwo Yee, Joan Ling, Rachel Kraut, Martin Wasser BMC Bioinformatics 2011, 12:232 (13 June 2011)

Research   Open Access

Creation of a novel telomere-cutting endonuclease based on the EN domain of telomere-specific non-long terminal repeat retrotransposon, TRAS1

Kazutoshi Yoshitake, Hideyuki Aoyagi, Haruhiko Fujiwara Mobile DNA 2010, 1:13 (1 April 2010)

Research article   Open Access

Using machine learning to speed up manual image annotation: application to a 3D imaging protocol for measuring single cell gene expression in the developing C. elegans embryo

Zafer Aydin, John I Murray, Robert H Waterston, William S Noble BMC Bioinformatics 2010, 11:84 (11 February 2010)

Methodology article   Open Access Highly Accessed

Edge detection in microscopy images using curvelets

Tobias Gebäck, Petros Koumoutsakos BMC Bioinformatics 2009, 10:75 (3 March 2009)

Research article   Open Access Highly Accessed

Lentivirus-mediated transgene delivery to the hippocampus reveals sub-field specific differences in expression

Lenneke WA van Hooijdonk, Muhammad Ichwan, Thomas F Dijkmans, Theo G Schouten, Marijke WA de Backer, Roger AH Adan, Fons J Verbeek, Erno Vreugdenhil, Carlos P Fitzsimons BMC Neuroscience 2009, 10:2 (13 January 2009)

Software   Open Access Highly Accessed

CellProfiler Analyst: data exploration and analysis software for complex image-based screens

Thouis R Jones, In Kang, Douglas B Wheeler, Robert A Lindquist, Adam Papallo, David M Sabatini, Polina Golland, Anne E Carpenter BMC Bioinformatics 2008, 9:482 (15 November 2008)

Research article   Open Access Highly Accessed

Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients

Kaleb M Pauley, Minoru Satoh, Annie L Chan, Michael R Bubb, Westley H Reeves, Edward KL Chan Arthritis Research & Therapy 2008, 10:R101 (29 August 2008)

MicroRNA expression in rheumatoid arthritis patients' peripheral blood mononuclear cells mimics that of synovial tissue and fibroblasts, and is a potentially useful marker for disease diagnosis, progression, or treatment efficacy.

Methodology article   Open Access Highly Accessed

Single cell cytometry of protein function in RNAi treated cells and in native populations

Peter LaPan, Jing Zhang, Jing Pan, Andrew Hill, Steven A Haney BMC Cell Biology 2008, 9:43 (1 August 2008)

Single cell cytometry can be successfully used to study the effects of RNAi in a mixed population of adherent cells, and to discern variations in function between individual cells within those cell cultures.

Research   Open Access Highly Accessed

Wndchrm – an open source utility for biological image analysis

Lior Shamir, Nikita Orlov, D Mark Eckley, Tomasz Macura, Josiah Johnston, Ilya G Goldberg Source Code for Biology and Medicine 2008, 3:13 (8 July 2008)