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Carpenter AE
Jones TR
Lamprecht MR
Clarke C
Kang IH
Friman O
Guertin DA
Chang JH
Lindquist RA
Moffat J
Golland P
Sabatini DM

on PubMed

Carpenter AE
Jones TR
Lamprecht MR
Clarke C
Kang IH
Friman O
Guertin DA
Chang JH
Lindquist RA
Moffat J
Golland P
Sabatini DM
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CellProfiler: image analysis software for identifying and quantifying cell phenotypes

Anne E Carpenter¹ , Thouis R Jones¹^,2 , Michael R Lamprecht¹ , Colin Clarke¹^,2 , In Han Kang² , Ola Friman³ , David A Guertin¹ , Joo Han Chang¹ , Robert A Lindquist¹ , Jason Moffat¹ , Polina Golland² and David M Sabatini¹^,4

¹Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA

²Computer Sciences and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02142, USA

³Department of Radiology, Brigham and Women's Hospital, Boston, MA 02115, USA

⁴Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA

author email corresponding author email

Genome Biology 2006, 7:R100doi:10.1186/gb-2006-7-10-r100


Published:	31 October 2006

Subject areas: Bioinformatics, Cell biology

Additional files

Additional data file 1:

CellProfiler manual

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Additional data file 2:

CellProfiler pipelines for experiments shown in this paper, listing the modules in the order used

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Additional data file 3:

CellProfiler modules by category, with their descriptions

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Additional data file 4:

Measurements made by CellProfiler modules

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Additional data file 5:

Data and image tools in CellProfiler, with their descriptions

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Additional data file 6:

Example from CellProfiler analysis of DNA content (cell cycle) in Drosophila Kc167 cells

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Additional data file 7:

Histograms of shape and texture features for wild-type cells

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Additional data file 8:

Measures for the cytoplasm-nucleus translocation assay (Figure 4) for which the Z' factor is above 0.5

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