Figure 2.

The MPI in the training and test cohorts. Heatmaps of relative gene expression (green = 'low', red = 'high') of the optimal 52-gene classifier and accompanying MPI distribution values across the three training cohorts (a) NKI2, (b) EMC and (c) NCH, and three test cohorts (d) JRH-1, (e) UPP and (f) JRH-2. The threshold shown for the MPI distributions was determined as explained in the text. Lower panels show the survival time distributions in the respective cohorts (black = 'death/poor outcome', grey = 'censored/good outcome').