Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial

Daniel G Lee^1,2,3 , Jonathan M Urbach^1,2 , Gang Wu^1,2 , Nicole T Liberati^1,2 , Rhonda L Feinbaum^1,2 , Sachiko Miyata^1,2 , Lenard T Diggins⁴ , Jianxin He^5,6 , Maude Saucier^5,6,7 , Eric Déziel^5,6,8 , Lisa Friedman^5,9 , Li Li¹⁰ , George Grills^10,11 , Kate Montgomery¹⁰ , Raju Kucherlapati¹⁰ , Laurence G Rahme^5,6 and Frederick M Ausubel^1,2

¹Department of Molecular Biology, Massachusetts General Hospital, Cambridge Street, Boston, Massachusetts, 02114, USA

²Department of Genetics, Harvard Medical School, Avenue Louis Pasteur, Boston, Massachusetts, 02115, USA

³Current address: Microbia, Inc., Bent Street, Cambridge, Massachusetts, 02141, USA

⁴Envivo Pharmaceuticals, Inc., Arsenal Street, Watertown, Massachusetts, 02472, USA

⁵Department of Microbiology and Molecular Genetics, Harvard Medical School, Longwood Avenue, Boston, Massachusetts, 02115. USA

⁶Department of Surgery, Massachusetts General Hospital, Fruit Street, Boston, Massachusetts, 02114, USA

⁷Current address: Université de Montréal, Station Centre-ville, Montréal, H3C 3J7, Canada

⁸Current address: INRS-Institut Armand-Frappier, boul. des Prairies, Laval, Quebec, H7V 1B7, Canada

⁹Current address: Cubist Pharmaceuticals, Inc., Hayden Avenue, Lexington, Massachusetts, 02421, USA

¹⁰Harvard Medical School - Partners Healthcare Center for Genetics and Genomics, Landsdowne Street, Cambridge, Massachusetts, 02139, USA

¹¹Current address: Core Facilities, Cornell University, Thurston Avenue, Ithaca, New York, 14850, USA