Pathway and gene-set activation measurement from mRNA expression data: the tissue distribution of human pathways

David M Levine¹ , David R Haynor² , John C Castle¹ , Sergey B Stepaniants¹ , Matteo Pellegrini³ , Mao Mao¹ and Jason M Johnson¹

¹Rosetta Inpharmatics LLC, a wholly owned subsidiary of Merck and Co., Inc., Terry Avenue North, Seattle, WA 98109, USA

²Department of Radiology, University of Washington, Seattle, WA 98195, USA

³Department of MCD Biology, University of California at Los Angeles, Los Angeles, CA 90095, USA