|
Distribution and Sec evolutionary trends of 25 bacterial selenoprotein families |
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| Selenoprotein family |
Number of selenoproteins |
Sec/Cys conversion events |
Selenoprotein loss events |
|
|
|
||||
| Sec→Cys |
Cys→Sec |
|||
|
|
||||
| Formate dehydrogenase alpha subunit (FdhA) |
103 |
7 |
- |
2 |
| Selenophosphate synthetase (SelD) |
38 |
3 |
- |
6 |
| Coenzyme F420-reducing hydrogenase delta subunit (FrhD)a |
19 |
3 |
3 |
5 |
| Heterodisulfide reductase, subunit A (HdrA)a |
16 |
- |
2 |
4 |
| Peroxiredoxin (Prx)a |
12 |
- |
5 |
- |
| HesB-like |
11 |
2 |
- |
3 |
| Glycine reductase selenoprotein A (GrdA) |
11 |
- |
- |
4 |
| Glycine reductase selenoprotein B (GrdB)a |
11 |
- |
- |
6 |
| SelW-likea |
10 |
- |
- |
3 |
| Prx-like thiol:disulfide oxidoreductasea |
8 |
- |
3 |
- |
| Thioredoxin (Trx)a |
7 |
- |
- |
- |
| Coenzyme F420-reducing hydrogenase α subunit (FrhA)a |
6 |
- |
2 |
- |
| Fe-S oxidoreductase (GlpC) |
5 |
- |
2 |
- |
| Proline reductase (PR)a |
5 |
- |
- |
- |
| DsbA-likea |
4 |
- |
1 |
1 |
| Glutaredoxin (Grx)a |
3 |
- |
3 |
- |
| Thiol:disulfide interchange proteina |
3 |
- |
1 |
- |
| AhpD-like (COG2128)a |
2 |
- |
2 |
- |
| ArsC-likea |
2 |
- |
1 |
2 |
| DsbG-likea |
2 |
- |
2 |
- |
| Distant AhpD homologa |
2 |
- |
1 |
- |
| Homolog of AhpF, amino-terminal domaina |
2 |
- |
2 |
1 |
| DsrE-likea |
1 |
- |
1 |
- |
| NADH oxidase |
1 |
- |
1 |
1 |
| Glutathione peroxidase (GPx)a |
1 |
- |
1 |
- |
|
|
||||
| Total |
285 |
15 |
33 |
38 |
|
aHomologs of thiol-based oxidoreductases. | ||||
Zhang et al. Genome Biology 2006 7:R94 doi:10.1186/gb-2006-7-10-r94 |
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