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Probe sets with altered transcriptional regulation after ethanol exposure with q < 0.001 |
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| Probe set ID |
p value |
Gene name |
Biological process |
Changes in expression |
|
|
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| 1623332_at |
1.91E-05 |
CG31106 |
Transmission of nerve impulse; carbohydrate metabolism |
Transient up-regulation |
| 1623605_a_at |
2.20E-05 |
Serpin-27A (M,H)* |
Toll signaling pathway; defense response |
Transient up-regulation |
| 1624662_at |
2.20E-05 |
CG11414 |
Protein ubiquitination |
Acute up-regulation |
| 1624736_a_at |
2.20E-05 |
CG11878 |
Unknown |
Slow up-regulation |
| 1625193_at |
2.20E-05 |
CG31272 |
Lipid metabolism; neurotransmitter secretion; transport |
Slow up-regulation |
| 1626882_at |
2.35E-05 |
Pinocchio |
Olfactory behavior;response to chemical stimulus |
Transient up-regulation |
| 1627080_at |
5.07E-05 |
CG14893 |
Unknown |
Slow up-regulation |
| 1627385_at |
6.86E-05 |
minidiscs |
Amino acid transport, metabolism |
Transient down-regulation |
| 1628229_at |
6.86E-05 |
Trypsin 29F |
Proteolysis |
Slow up-regulation |
| 1628494_a_at |
6.86E-05 |
CG33525 |
Negative regulation of transcription, DNA-dependent |
Slow up-regulation |
| 1628647_at |
1.06E-04 |
CG33110 |
Fatty acid biosynthesis; very-long-chain fatty acid metabolism |
Slow up-regulation |
| 1628947_s_at |
1.06E-04 |
Ecdysone-inducible gene L2 (M,H)* |
Cell adhesion |
Acute up-regulation |
| 1629012_at |
1.06E-04 |
period (M,H)* |
Long-term memory; circadian rhythm; signal transduction; negative regulation of transcription from RNA polymerase II promoter |
Transient down-regulation |
| 1629592_at |
1.32E-04 |
ηTrypsin (M,H)* |
Proteolysis |
Transient down-regulation |
| 1629617_at |
1.44E-04 |
cabut |
Regulation of transcription from RNA polymerase II promoter; JNK cascade; autophagic cell death |
Acute up-regulation |
| 1630302_at |
1.66E-04 |
Odorant-binding protein 99d |
Transport; autophagic cell death |
Slow up-regulation |
| 1631406_at |
1.66E-04 |
CG3106 (M,H)* |
Unknown |
Transient down-regulation |
| 1632222_a_at |
2.25E-04 |
CG17752 |
Extracellular transport; cation transport |
Slow up-regulation |
| 1632228_at |
2.58E-04 |
CG10505 |
Response to toxin; extracellular transport; defense response |
Slow up-regulation |
| 1633700_at |
2.78E-04 |
antennal protein 10 (M,H)* |
Sensory perception of chemical stimulus |
Acute down-regulation |
| 1633794_a_at |
3.22E-04 |
antennal protein 5 |
Signal transduction |
Acute down-regulation |
| 1633913_at |
3.80E-04 |
Cytochrome P450-6a8 |
Electron transport; steroid metabolism; lauric acid metabolism |
Slow up-regulation |
| 1634318_at |
3.98E-04 |
lush |
Response to ethanol; sensory perception of smell; olfactory behavior |
Acute down-regulation |
| 1634591_at |
4.38E-04 |
Rpd3 |
Regulation of transcription from RNA polymerase II promoter; determination of adult life span; gene silencing |
Slow up-regulation |
| 1635815_at |
5.47E-04 |
CG5819 (M,H)* |
Transmission of nerve impulse; cell adhesion |
Acute up-regulation |
| 1636202_s_at |
6.40E-04 |
CG8931 |
Transport |
Transient up-regulation |
| 1636611_at |
6.40E-04 |
Pheromone-binding protein-related protein 1 (M)* |
Signal transduction; sensory perception; response to pheromone |
Acute down-regulation |
| 1636771_at |
6.40E-04 |
CG8562 |
Proteolysis |
Slow down-regulation |
| 1638066_at |
6.40E-04 |
CG9238 |
Glycogen metabolism |
Slow up-regulation |
| 1638246_at |
6.52E-04 |
Olfactory-specific E |
Signal transduction; response to pheromone; transport |
Acute down-regulation |
| 1638452_at |
7.01E-04 |
CG6733 |
Proteolysis |
Slow down-regulation |
| 1639368_at |
7.73E-04 |
CG5804 |
Lipid transport; cell acyl-CoA homeostasis |
Transient down-regulation |
| 1639934_at |
7.77E-04 |
capulet |
Actin filament organization; bristle morphogenesis |
Slow up-regulation |
| 1640755_at |
8.83E-04 |
Picot |
Phosphate metabolism; extracellular transport; cation transport |
Slow up-regulation |
|
Transcripts that show sustained altered expression after the first exposure to ethanol are indicated as 'acutely up- or down-regulated genes'. Transcripts that show altered expression only after the second exposure are designated as 'slowly up- or down-regulated genes'. The designation 'transient up-regulation' refers to genes that show increased expression after the first exposure to ethanol, but a return to control levels 2 h later after the second exposure. *Genes that have human (H) and/or mouse (M) orthologues. | ||||
Morozova et al. Genome Biology 2006 7:R95 doi:10.1186/gb-2006-7-10-r95 |
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