Additional data file 1:

The first line contains abbreviations describing the column content: YORF, yeast open reading frame ID; Gene, gene symbol of yeast gene; Hs, orthology to human nucleolar protein; At, orthology to mouse ear cress nucleolar protein; It, link to nucleolar protein via Y2H interaction in Ito dataset; Ue, link to nucleolar protein via Y2H interaction in Uetz dataset; Ga, link to nucleolar protein via participation in a complex in Gavin data set; Ho, link to nucleolar protein via participation in a complex in Ho data set; Kr, link to nucleolar protein via participation in a complex in Krogan data set; log(O), average posterior odds ratio O_post from all cross-validation runs (note that the proteins served as positive training cases); Pred., prediction result (nucleolar or not) according to a majority vote based on all cross-validation runs; Desc., concise description of protein function.

Format: TXT Size: 461KB Download file

Additional file 2:

The first line contains abbreviations describing the column content. Gene, gene symbol of yeast gene; ORF, yeast open reading frame ID; Hs, orthology to human nucleolar protein; At, orthology to mouse ear cress nucleolar protein; It, link to nucleolar protein via Y2H interaction in Ito dataset; Ue, link to nucleolar protein via Y2H interaction in Uetz dataset; Ga, link to nucleolar protein via participation in a complex in Gavin data set; Ho, link to nucleolar protein via participation in a complex in Ho data set; Kr, link to nucleolar protein via participation in a complex in Krogan data set; log(O), average posterior odds ratio from all prediction runs in which the protein was not used for training; Desc., concise description of protein function. The listed proteins were all predicted to be not nucleolar based on a threshold of O_post < 0.4.

Format: TXT Size: 34KB Download file