Table 4

Prediction of the size of the human interactome

Dataset pair

Interactions in both datasets

Estimated interactions in common search space

Projected interactome size (95% CI)

Rual-Lehner (core) [14,40]

35

28,200

261,000 (191,000-369,000)

Rual-Rhodes [14,23]

59

20,200

189,000 (154,000-239,000)

Mean

225,000 (154,000-369,000)*

*The range of interactome sizes is the minimum and maximum from the confidence intervals (CI) generated from pairwise estimates.

Hart et al. Genome Biology 2006 7:120   doi:10.1186/gb-2006-7-11-120